Projects

O-GlcNAcylation in AML

A project focused on implicating the Hexoseamine Biosynthetic Pathway and O-GlcNAcylation in AML. We collected a large amount of publicly available data from NCI, St. Jude Children’s Research Hospital, and the NIH GEO to investigate expression of Hexoseamine Biosynthetic Pathway members across AML patient samples and healthy controls.

Code on GitHub Publication

Pediatric AML Survival Prediction

We wanted to find an approach to predict pediatric FLT3-ITD AML survival. We used CIBERSORTx as a feature extractor for bulk RNA sequencing data using a custom reference generated from single-cell RNA sequencing data generated in the lab. We found this increased prediction accuracy.

AACR 2022 Abstract

Sorting Students into Random Groups

A simple project to make a CLI and GUI to sort students into groups using Rust. The purpose was:

  • I wanted for someone to be able to run this without having R or Python installed,

  • Learn a little bit of a compiled language, and

  • My fianceé had a use for such a utility.

Code on GitHub